• Phoenixz@lemmy.ca
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    24 minutes ago

    If you talk about killing the few people like these that are the root cause of all these problems, you’re a terrorist. You go to jail

    These people actually kill people by the thousands, millions, and we call them smart CEO’s and celebrate them 🥂

  • Zacryon@feddit.org
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    2 hours ago

    Naive question from a european: Aren’t there companies on the market who can offer a cheaper price and therefore beat greedy competitors?

    • fullsquare@awful.systems
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      14 minutes ago

      the problem is that there is natural (as in, unmodified) cheap generic insulin available, it’s just that it sucks compared to everything else. you see, insulin is a peptide that is supposed to appear, do some signalling, then disappear and unmodified insulin copies this thing exactly. the problem is, most of the time when peptide is supposed to work as a pharmaceutical, you don’t want to do that, you’d like insulin to last longer than usual, which means changes to it that make breakdown slower, or adding something that makes it stick to albumin, which has similar effect because it hides insulin somewhere enzymes can’t reach it and also it makes it start acting slower. this means less frequent dosing and less changes in insulin activity over time. there are also other insulins that start acting faster than natural, and this is also due to a couple of modifications in its structure

      for another example, ozempic was not the first drug in its class, it’s also a modified peptide, and it can be injected s.c. once a week, compared to previous iteration (liraglutide) that requires daily injections. if natural peptide is injected i.m. instead, its halflife is half an hour, and in serum it’s only two minutes (it gets released a bit slower than it is metabolized)

      manufacturing costs are about the same for any variant, most of it is in purification. patents for a couple of these have expired anyway by now, but if manufacturing is limited then price can be set arbitrarily high (see daraprim)

    • Soulg@ani.social
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      1 hour ago

      Correct, but when it’s already been established that people will pay those prices, they keep them high. So instead of going from $800 to $5 out of the goodness of their hearts, they go from $800 to $650 (number made up) to get more business but still make massive profits.

      • Banana@sh.itjust.works
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        1 hour ago

        Doesn’t work when people don’t get to choose not to take it when it gets too expensive! That thing that capitalists always forget about: necessities.

        • Natanox@discuss.tchncs.de
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          29 minutes ago

          Every time someone talks about you being supposedly free to choose where to work they should get instant diarrhea. Let alone medicine of course, that’s a hard dependence.

          Nobody is truly free without proper UBI and free healthcare and good public transport. Only then true freedom can exist.

    • hakase@lemmy.zip
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      2 hours ago

      Yup, but their products don’t work as well, don’t work for everyone, or have other downsides. Banting’s original insulin would be dirt cheap today, but it’s shit compared to what we have now, so the best products on the market today charge a premium for either efficacy or convenience.

  • macncheese@lemmy.world
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    3 hours ago

    California is contracting its own insulin supply and it’ll be available for $11 a pen starting Jan 1, 2026. I know not every state can or are willing to do this but just throwing out some examples and hopefully optimism to somehow fight the American decline from within it. We’re in a unique position as our state economy is larger than most countries but I am hopeful we will throw our weight around to counter the bs. https://www.chhs.ca.gov/blog/2025/10/17/governor-newsom-announces-affordable-calrx-insulin-11-a-pen-will-soon-be-available-for-purchase/

  • Wild_Mastic@lemmy.world
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    4 hours ago

    Meanwhile, 10 euros per vial here in Europe. At least his original plan for widespread and easy availability has partially succeeded.

    • ChilledPeppers@lemmy.dbzer0.com
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      2 hours ago

      In brazil 36 reais (about 6 euro). The US is a joke. (And im 99% sure you can also get it for free if you use the public health network)

      • mika_mika@lemmy.world
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        26 minutes ago

        I have mental health disabilities in the USA and my meds are at zero cost because I literally have had absolute zero income for the past 5 years.

        You wouldn’t believe how much those mood stabilizer/antidepressant cocktails stack up proportionally when I was able to scrape by on $15 an hour.

        The system set me up to fail with how shitty it is, if healthcare wasn’t crap I could be contributing to society without crippling myself.

  • BootLoop@sh.itjust.works
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    1 hour ago

    Canadians: invented drug and patent it freely

    Americans: Finds way to kill the most people possible while making the most amount of money

    • Phil_in_here@lemmy.ca
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      4 hours ago

      To be fair, the killing isn’t the point; they’re the product. Its just that profit is God, so killing in its name is justified.

      Killing poors for the joy of it? That’s just an evil bonus.

  • ryannathans@aussie.zone
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    Soo why sell the patent for $1 and have it be potentially exploited when you could hold onto it and licence use for free?

    • boonhet@sopuli.xyz
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      4 hours ago

      IIRC the insulin being sold now is manufactured differently and the patents are completely different anyway

      But overall your point is good

          • JasonDJ@lemmy.zip
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            2 hours ago

            This is a great way of phrasing things.

            Services that are necessary for life (like healthcare)…if other countries have figured out how to make it affordable/free (at point of use), any person or industry that tries to extract profit out of it is literally anti-American.

        • A_Union_of_Kobolds@lemmy.world
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          3 hours ago

          Bingo. It’s extortion and if the asshat in charge gave any kind of a real fuck about cheap medicine it should’ve been a day 1 fix.

      • thesystemisdown@lemmy.world
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        3 hours ago

        The insulin produced now has benefited from advances in technology just like most things. The fast acting insulin is predictable and works in 45 minutes to an hour and a half. The original insulin took hours and wasn’t nearly as predictable or stable. Testing/monitoring technology has seen even more significant advances.

        I owe Banting and his colleagues my life, but it is different. That’s not to say that the continued well being of the public should be profitable and exclusive.

        • mirshafie@europe.pub
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          I mean insulin is about 10x more expensive in the USA compared to other Western countries. It’s cheaper still in lower income countries. Many European countries also have a price ceiling for medication, so your monthly cost for life-saving drugs is capped.

          I don’t know exactly why a manufacturer doesn’t set up production for much cheaper generics in the USA, but for whatever reason Americans are getting price gouged like Satan doesn’t believe in tomorrow.

          • icelimit@lemmy.ml
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            3 hours ago

            Whatever reason? Simple reason: legal to maximize profits over people’s misfortunes.

            • Bubbaonthebeach@lemmy.ca
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              3 hours ago

              To be fair, most Americans agree with the capitalist first approach right up until it affects them individually. If they were willing to help each other instead of believing that anyone other than themself is a freeloader and lazy, they would have the support that other countries take for granted.

              • GuyLivingHere@lemmy.ca
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                6 minutes ago

                They wouldn’t be ‘freedom loving’ or ‘American’ if they actually gave a shit about other people.

    • TheJesusaurus@sh.itjust.works
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      3 hours ago

      It was sold to a Canadian public university to manage the patent for public good.

      They have, everywhere else in the world basically, insulin costs pennies.

      In America, they have been able to patent certain formulations and delivery methods, and they keep making marginal modifications to string the patents out to keep Americans locked in to absurd insulin prices.

      Was that the answer you thought it was going to be?

  • TheLeadenSea@sh.itjust.works
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    5 hours ago

    I wondered if all the sane Americans did a mass exodus to Canada, Europe, UK, Australia etc, what effect that would have

    • turdcollector69@lemmy.world
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      It’s already happening, there’s been a deluge of affluent people leaving the US.

      We’re still at the stage where it takes considerable privilege to just leave everything behind and pay the exit extortion (40% of all your shit).

      Once things get worse and people have nothing to leave behind you’ll start seeing the engineers/doctors escaping.

    • PunnyName@lemmy.world
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      5 hours ago

      A lot of us would need financial sponsorship. So there’d be a literal financial drain on those economies.

      I still would like to sign up.

      • Soup@lemmy.world
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        4 hours ago

        Not if you stayed, then it’s an investment. Money doesn’t just disappear when goes to poor people, they use it to buy things like food and stuff. It would only be a financial drain if you were sending that money back home.

        The North American mind cannot comprehend the benefits of supporting the poor.

        • Warl0k3@lemmy.world
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          Perhaps strain would be a better word than drain - it would still be a short-mid term financial burden to take even a tiny fraction of the sane population from the US, it’s a big country. Sure would be nice if it could be arranged though…

        • PunnyName@lemmy.world
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          3 hours ago

          I get that, the initial investment would be pretty significant.

          I’m not against it of course, I just think it’s necessary to understand the risks of any gamble.

    • Pennomi@lemmy.world
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      4 hours ago

      Have you looked into what it takes to get a permanent visa to one of those countries? It’s not easy.

        • Pennomi@lemmy.world
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          2 hours ago

          It is that hard, I’ve looked. You typically need to rank highly on a skill list AND have a relatively well-paying job offer. And if you think it’s hard interviewing in your own country, it’s far worse interviewing outside of it.

          • Fizz@lemmy.nz
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            What are you comparing it to? Americans have a much easier path to permanent residency than a vast majority of the world.

            Take a look at the skills lists they aren’t that insane. Also you dont need to go straight for permanent residency you can start with a working visa which is easy to get.

        • fossilesque@mander.xyzOPM
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          4 hours ago

          You have to earn over something like 100k+ for the US to tax you. Salaries are lower here.

        • idiomaddict@lemmy.world
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          4 hours ago

          You still have to file, but you don’t need to pay taxes unless you’re earning enough that the visa won’t be a problem.

          But, like, if you close everything out and never go back…

            • idiomaddict@lemmy.world
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              3 hours ago

              But then what?

              Is a foreign government going to extradite you for missing paperwork and no outstanding tax debts (especially because everyone else thinks it’s nuts that we require nonresident citizens to file taxes)? I guess it’s possible, but it strikes me as very unlikely.

              But if you’re still financially attached to the US/likely to visit, they’ve got some power over you.

              I’m not a lawyer or an accountant (obviously. This is not best practices)

              • turdcollector69@lemmy.world
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                1 hour ago

                Why would that strike you as unlikely? It’s extremely likely because most countries that people would want to flee to already have extradition agreements with the US.

                All the US has to do is declare you a fugitive and those countries will pick you up and ship you back.

                Especially with how petty this administration has been.

  • Elgenzay@lemmy.ml
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    3 hours ago

    Shoutout to the uninsured cost of the medication I need to live

    (90 tablets)

    • ameancow@lemmy.world
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      3 hours ago

      I would literally move if I could afford it and if it was even a little easier.

      Stockholm syndrome suggests we enjoy it or want to be here.

    • PM_ME_VINTAGE_30S [he/him]@lemmy.sdf.org
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      Reminder that the term Stockholm Syndrome was coined to blame victims for being rightly more afraid of the police than their captors:

      In [Jess Hill’s] 2019 treatise on domestic violence See What You Made Me Do, Australian journalist Jess Hill described the syndrome as a “dubious pathology with no diagnostic criteria”, and stated that it is “riddled with misogyny and founded on a lie”; she also noted that a 2008 literature review revealed “most diagnoses [of Stockholm syndrome] are made by the media, not by psychologists or psychiatrists.” In particular, Hill’s analysis revealed that Stockholm authorities, responded to the robbery in a way that put the hostages at greater risk from the police than from their captors (hostage Kristin Enmark, who during the siege was granted a telephone call with Swedish Prime Minister Olof Palme, reported that Palme told her that the government would not negotiate with criminals); as well, she observed that Bejerot’s diagnosis of Enmark was made without ever having spoken to her.

      Otherwise, we probably agree that AmeriKKKans are a feckless, servile people.

      • mirshafie@europe.pub
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        3 hours ago

        Nils Bejerot was a total hack. He tried to ban comic books, and later transcribed that same energy in a war on drugs that has resulted in some of the worst health outcomes for drug users in Europe. Unfortunately his ability to be confidently incorrect swayed a lot of gullible rubes, and his legacy still casts a shadow over Sweden to this day.

      • QuinnyCoded@sh.itjust.works
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        4 hours ago

        Stockholm syndrome is a proposed condition to explain why hostages occasionally develop a psychological bond with their captors. It is named after an attempted bank robbery in 1973, in Stockholm, Sweden

        ?

        • PM_ME_VINTAGE_30S [he/him]@lemmy.sdf.org
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          3 hours ago

          My comment was in response to a comment about AmeriKKKans having “Stockholm Syndrome”, which as it turns out is not a real or valuable diagnosis. However, I do not disagree with the implied critique of AmeriKKKan people as being feckless and servile people.

          • turdcollector69@lemmy.world
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            55 minutes ago

            You lost me with thebrepeated “amerikkkan” thing.

            A: It completely undercuts the seriousness of your comment and makes the whole thing come off as a tirade by an edgy teenager.

            B: Jokes don’t get funnier every time you repeat them, it was mid the first time and eye roll worthy by the 3rd.

            I agree with your points, just sucks that you chose to present it in such a juvenile way.

            • dickalan@lemmy.world
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              48 minutes ago

              Boo-hoo buddy who the fuck cares, clearly you do and you felt the need to tell everybody on the net like a fucking baby

              • turdcollector69@lemmy.world
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                12 minutes ago

                Wow such maturity, this is why nobody takes tankies seriously.

                Don’t worry when you grow up and learn how to communicate effectively people will listen to you.

                • dickalan@lemmy.world
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                  6 minutes ago

                  The fuck did you just call me weirdo quit trying to fucking put me in a box, fuck off

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        4 hours ago

        AmeriKKKans

        whoa! so edgy, poignant, and relevant!
        and so creative!
        amazing!
        *and everyone clapped*

        • PM_ME_VINTAGE_30S [he/him]@lemmy.sdf.org
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          AmeriKKKa is a settler-colonialist project, and the entity and its defenders deserve zero respect. I mentioned AmeriKKKans because the person I replied to used Stockholm Syndrome to critique AmeriKKKans on a post critiquing the AmeriKKKan healthcare system, so critiquing AmeriKKKa is relevant here. And I don’t like spelling AmeriKKKa as part of USA correctly because (1) places like Central America and South America should be distinguished from the United States of AmeriKKKa, and (2) it offends the people who need to be offended, i.e. people who still feel affinity for the AmeriKKKan project and people who tone-police others who are just brutally honest in speaking their minds.

          You are literally posting from an anarchist Lemmy instance, why TF is this controversial to you?

          • ozymandias@lemmy.dbzer0.com
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            3 hours ago

            wow, each time you write “AmeriKKKa” you just get so so much smarter.
            it makes me really care about what else you have to say… so so much!

            • dickalan@lemmy.world
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              47 minutes ago

              It’s funny how you can russlr your Jimmy’s just by saying a simple word, you wouldn’t have to be Conservative weirdo are you

  • lmmarsano@lemmynsfw.com
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    Needs text alternative.

    Images of text break much that text alternatives do not. Losses due to image of text lacking alternative such as link:

    • usability
      • we can’t quote the text without pointless bullshit like retyping it or OCR
      • text search is unavailable
      • the system can’t
        • reflow text to varied screen sizes
        • vary presentation (size, contrast)
        • vary modality (audio, braille)
    • accessibility
      • lacks semantic structure (tags for titles, heading levels, sections, paragraphs, lists, emphasis, code, links, accessibility features, etc)
      • some users can’t read this due to lack of alt text
      • users can’t adapt the text for dyslexia or vision impairments
      • systems can’t read the text to them or send it to braille devices
    • web connectivity
      • we have to do failure-prone bullshit to find the original source
      • we can’t explore wider context of the original message
    • authenticity: we don’t know the image hasn’t been tampered
    • searchability: the “text” isn’t indexable by search engine in a meaningful way
    • fault tolerance: no text fallback if
      • image breaks
      • image host is geoblocked due to insane regulations.

    Contrary to age & humble appearance, text is an advanced technology that provides all these capabilities absent from images.

    Did they try looking for discounts from patient assistance programs from the manufacturer? They’ll reduce the cost to $35.

    Manufacturers try to shakedown insurance companies for obscene pay without affecting the amount individuals pay, so they offer those programs directly to individuals. Not saying this good, just how the system works.

  • greedytacothief@lemmy.dbzer0.com
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    3 hours ago

    If I’m remembering the original sysntesis for insulin used dogs, and it was harvest from them after being killed. It’s unjust that insulin is so expensive, but also modern production methods are not the problem here. It’s greed.

      • cassandrafatigue@lemmy.dbzer0.com
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        2 hours ago

        No. They kill us. They murder people. Make it clear why this is happening, why any negotiation starts with every billionaire shot in the gut and left to bleed out, as a compromise.

        • ameancow@lemmy.world
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          51 minutes ago

          I hope you understand anonymity is an illusion and that intelligence agencies and law enforcement can use these kinds of comments as a justification to get ALL up in your shit. This kind of performative “we got a badass over here” act is not really impressing anyone here, and it could get you in massive trouble.

          This isn’t the internet’s backwater. There are bots crawling through these comments right now looking for and flagging users.