• FishFace@piefed.social
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    11 days ago

    Besides size, that looks of tolerance is exactly the insight. It doesn’t come from birth.

    • theneverfox@pawb.social
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      10 days ago

      It does come from birth though? Genetics play a huge part role in alcohol processing

      Practice doesn’t make you metabolize the alcohol much faster, it makes you better at functioning at a higher BAC, it increases tolerance not metabolism

      • FishFace@piefed.social
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        10 days ago

        I don’t know how much faster it gets, but consuming alcohol increases the expression of alcohol dehydrogenase, so you metabolise it faster.

        • theneverfox@pawb.social
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          9 days ago

          Yeah, obviously. Do you think your body is at maximum alcohol detox levels at all times? Of course not, that’s one part of the detox pathway that fires up when you start drinking

          How long do you think enzymes stick around? Do you think they pile up?

          Their expression is generally linked to presence of a trigger and limited by their byproducts. So you’ll produce more of them when exposed to alcohol, then max out based on how quickly the byproducts can be moved

          Again, how quickly you process alcohol is mostly genetics

    • CallMeAnAI@lemmy.world
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      11 days ago

      You don’t think people have different metabolic tolerance and processing rates?

      🤯

      • FishFace@piefed.social
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        10 days ago

        They do, but nobody’s sinking 210ml of pure ethanol and blowing that low without either being the size of a house or putting in some serious practice. That’s the same as drinking 2 entire bottles of wine in 2 hours.

        It’s the practice they were talking about with “insight”.