I only skimmed this article but seems to suggest that’s not a major concern with their treatment.
Pieper emphasized that current over-the-counter NAD±precursors have been shown in animal models to raise cellular NAD+ to dangerously high levels that promote cancer. The pharmacological approach in this study, however, uses a pharmacologic agent (P7C3-A20) that enables cells to maintain their proper balance of NAD+ under conditions of otherwise overwhelming stress, without elevating NAD+ to supraphysiologic levels.













“Magic system” is a bit of an oxymoron imo. The problem with having hard rules for magic is that that’s not magic, that’s science. You just end up with a world with slightly different physical laws.
Technology can be interesting on its own but a deep understanding of the underlying mechanics kills the magic. A rock that lets you talk with someone over great distance is magic but if you explain it as manipulating imperceptible vibrations in the air you just have a radio.