Common Supplement Shows Concerning Link to Heart Failure
www.sciencealert.com
New research into a popular sleeping aid has some scientists worried about long-term usage.

Among more than 130,000 adults across multiple countries, those who were prescribed melatonin long-term had an 89 percent higher risk of heart failure over five years, and were twice as likely to die from any cause, compared with those not prescribed melatonin.

  • AbouBenAdhem@lemmy.worldEnglish
    22·
    2 days ago

    We queried the TriNetX Global Research Network for adults ≥ 18 years with an insomnia diagnosis (ICD-10 F51.0). The exposed cohort required ≥ 1 melatonin prescription and ≥ 365 exposure-days; controls had no melatonin exposure.

    I interpret that to mean that both the study and control cohorts had insomnia diagnoses, but the cohorts weren’t randomized and no other variables were controlled for.