Research identifies protein responsible for increasing inflammation and oxidative stress

A new study has identified a protein that nicotine-free vape fluid increases in the lung, causing damage including oxidative stress, inflammation and breakdown of the blood vessels.

The research, published in the journal Microvascular Research demonstrates a range of damaging pathways when an in vitro model of the human lung was exposed to a common brand of nicotine-free e-cigarette.

E-cigarettes have become increasingly popular in recent years and are often seen as harmless alternatives to cigarette smoking. It is estimated that there are almost five million ‘vapers’ in the UK, compared to around 700,000 in 2012.

  • chicken@lemmy.dbzer0.com
    link
    fedilink
    arrow-up
    0
    ·
    9 months ago

    Three vapes, all watermelon flavour, were purchased from an online retailer and contained different concentrations of nicotine: 0mg, 10mg and 20mg in a 2ml solution

    • ArcaneSlime@lemmy.dbzer0.com
      link
      fedilink
      arrow-up
      1
      ·
      edit-2
      9 months ago

      Where the fuck can I buy 2ml of 20mg liquid? Standard these days since the dawn of mods is 3mg or 6mg, back around 2012ish you could get 3mg, 6mg, 12mg, 18mg, or 24mg, 10 or 20mg has never been a standard. On top of that the smallest bottle I’ve seen sold is 5ml testers, who the fuck sells 2ml?!

      Even salt nic, it’s usually 25-50mg. 20mg salt nic would make sense but where the dick do I buy a 2ml bottle? That’s barely a bottle at that point it’s a damn vial, nobody sells that shit. Salt nic bottles are usuall all 30ml, never seen a 5ml, 60ml, or 120ml.

      I’m gonna need this study to link me to the online retailer, because frankly I’m not sure I believe them.

      • shottymcb@lemm.ee
        link
        fedilink
        arrow-up
        1
        ·
        edit-2
        9 months ago

        Those are standard strengths for freebase nicotine. Nicotine salt comes in different strengths. 50mg/ml and 35mg/ml are standard where I live in the US. Elfbars usually come in 40mg/ml.

      • Onsotumenh@discuss.tchncs.de
        link
        fedilink
        arrow-up
        1
        ·
        edit-2
        9 months ago

        Probably a European pod they’re often around 2ml. Maximum nicotine concentration here is 20mg/ml independent of buying a nicotine shot for mixing liquid yourself, or buying a ready to use flavoured one. Yuul responded to this limit by increasing it’s wick size and effectively increasing nicotine levels per hit above the American levels (of course using up pods much faster is a welcome side effect).

        Edit: just look at the top sellers here for example https://www.dampfalarm.de/E-Zigaretten/Pod-Systeme/?p=1