Hear me out. A few games have shader installations that will usually apply any new settings you put down AFTER you restart the game, and a lot of other games have graphics settings that will only apply after you’ve rebooted the game.
I don’t think it would cost developers ANY amount of money or any significant development time to add a “Reboot game” button (or toggle) every time the player presses the quit button, or give the player a prompt every time they change a setting that requires a game restart (like in both PC versions of GTA V).
I also think ANY game should have a “full potato” mode capable of running in older computers with NONE of the fancy graphics stuff that we have access to today, despite having a decent computer now.
I can’t think of a setting that would universally apply to all games, like I’d be hard pressed to say a setting in Tetris that would apply to Minecraft. Vision and auditory accessibility is probably about it, but those settings would look pretty different I think depending on the game or genre of game.